SCHEMBL30826320

SCHEMBL30826320

c1cc(-c2sc(-c3ccncc3)c3c2OCCO3)ccn1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.54
MAPT P10636 2/20 0.54
CYP3A4 P08684 2/20 0.54
CYP2D6 P10635 2/20 0.54
CYP2C9 P11712 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2C19 P33261 1/20 0.54
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.35
PKM P14618 1/20 0.35
NISCH Q9Y2I1 1/20 0.35
NOTUM Q6P988 1/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
HSD17B10 Q99714 2/20 0.34
MAPK14 Q16539 3/20 0.34
ROCK1 Q13464 2/20 0.34
ROCK2 O75116 1/20 0.34
PRKCI P41743 1/20 0.33
PRF1 P14222 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19899441 0.85 MAPT (0.41) KDM4EMAPTCYP3A4CYP2D6CYP2C9
SCHEMBL2576798 0.77 ITGB2 (0.37) MAPTCYP2D6CYP1A2CYP2C19LMNA
SCHEMBL4138079 0.77 XDH (0.39) KDM4EMAPTCYP3A4CYP2D6CYP2C9
SCHEMBL22793727 0.75 KDM4E (0.39) KDM4EMAPTLMNAPKMNISCH
SCHEMBL30509710 0.75 XDH (0.35) KDM4EMAPTLMNATP53ALDH1A1
SCHEMBL4134447 0.75 XDH (0.38) KDM4EMAPTCYP3A4CYP2D6CYP2C9
SCHEMBL4143933 0.72 XDH (0.34) XDH
SCHEMBL15150098 0.70 KDM4E (1.00) KDM4EMAPTCYP3A4CYP2D6CYP2C9
SCHEMBL23485254 0.70 CDC7 (0.38) KDM4EMAPTCYP3A4CYP2D6CYP2C9
SCHEMBL23485236 0.69 CDC7 (0.39) KDM4EMAPTCYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700457-A Electrochromic compound, preparation method and application 北京大学深圳研究生院 2024-03-15 CN disclosed