Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18005467 | 1.00 | PDE10A (0.44) | PDE10AHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL18005408 | 0.98 | PDE10A (0.46) | PDE10AHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL18005482 | 0.96 | PDE10A (0.46) | PDE10AHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL18005631 | 0.84 | HTR1A (0.40) | PDE10AHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL18005335 | 0.83 | HTR1A (0.40) | PDE10AHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL18029842 | 0.83 | HTR1A (0.40) | PDE10AHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL19899798 | 0.82 | KCNH2 (0.38) | FFAR4KCNH2CDK1CDK2 | |
| SCHEMBL19900149 | 0.82 | KCNH2 (0.38) | FFAR4KCNH2CDK1CDK2 | |
| SCHEMBL19900123 | 0.81 | HRH4 (0.40) | PDE10ADRD2HTR6FFAR4KCNH2 | |
| SCHEMBL18005398 | 0.78 | SPHK1 (0.35) | FFAR4KCNH2CDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018039077-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-01 | — | — | WO | disclosed |