Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19899737 | 1.00 | CHRM3 (0.32) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19900142 | 0.86 | NPY5R (0.31) | NPY5RCHRM1 | |
| SCHEMBL19900313 | 0.86 | NPY5R (0.31) | NPY5RCHRM1 | |
| SCHEMBL19899762 | 0.82 | MEN1 (0.32) | — | |
| SCHEMBL19900507 | 0.82 | MEN1 (0.32) | — | |
| SCHEMBL18005617 | 0.79 | CHRM1 (0.30) | CHRM1 | |
| SCHEMBL19900683 | 0.79 | CHRM1 (0.30) | CHRM1 | |
| SCHEMBL19900182 | 0.77 | NPY5R (0.36) | PDE4APDE4BPDE4CPDE4DNPY5R | |
| SCHEMBL19900162 | 0.77 | NPY5R (0.36) | PDE4APDE4BPDE4CPDE4DNPY5R | |
| SCHEMBL18005537 | 0.77 | MEN1 (0.32) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018039077-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-01 | — | — | WO | disclosed |