Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900182 | 1.00 | NPY5R (0.36) | NPY5RMEN1KMT2ALMNAADORA2A | |
| SCHEMBL18005455 | 0.86 | ATM (0.39) | NPY5RMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL19900131 | 0.83 | NPY5R (0.36) | NPY5RMEN1KMT2ALMNATLR9 | |
| SCHEMBL19899801 | 0.83 | NPY5R (0.36) | NPY5RMEN1KMT2ALMNATLR9 | |
| SCHEMBL18005354 | 0.82 | MEN1 (0.36) | MEN1KMT2ALMNASMN1; SMN2NPSR1 | |
| SCHEMBL18005469 | 0.81 | SMN1; SMN2 (0.35) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL19899737 | 0.77 | CHRM3 (0.32) | NPY5RPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18005617 | 0.77 | CHRM1 (0.30) | CHRM1 | |
| SCHEMBL19900198 | 0.77 | CHRM3 (0.32) | NPY5RPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19900683 | 0.77 | CHRM1 (0.30) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11390605-B2 | Substituted pyrimidine compounds as multifunctional radical quenchers and their uses | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2022-07-19 | — | — | US | disclosed |
| US-20210276979-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-09-09 | — | — | US | disclosed |
| WO-2018039077-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210276979-A1 | THERAPEUTIC COMPOUNDS | CFTR, F12, FURIN | NPY5R 1478/4885MEN1 144/4885KMT2A 4374/4885 |
| US-11390605-B2 | Substituted pyrimidine compounds as multifunctional radical quenchers and their uses | DPYD, TYMP, NUDT1 | NPY5R 2206/4885MEN1 2429/4885KMT2A 3315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.