SCHEMBL19900665

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30437437	1.00	MAPT (0.60)	MAPTTP53HPGDTSHRMAPK1
	SCHEMBL2002892	0.92	NR1H4 (0.54)	MAPTTP53TSHRALDH1A1POLB
	SCHEMBL19899890	0.92	MAPT (0.49)	MAPTTP53HPGDTSHRMAPK1
	SCHEMBL19901002	0.89	TP53 (0.47)	MAPTTP53HPGDTSHRMAPK1
	SCHEMBL19899941	0.89	NR1H4 (0.49)	MAPTTP53TSHRALDH1A1GAA
	SCHEMBL30437657	0.89	TP53 (0.47)	MAPTTP53HPGDTSHRMAPK1
	SCHEMBL30437182	0.89	NR1H4 (0.49)	MAPTTP53TSHRALDH1A1GAA
	SCHEMBL19900647	0.88	TP53 (0.46)	MAPTTP53HPGDTSHRMAPK1
	SCHEMBL2003228	0.88	NR1H4 (0.50)	MAPTTP53HPGDTSHRALDH1A1
	SCHEMBL2004785	0.88	NR1H4 (0.50)	MAPTTP53HPGDTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.