FXR1

RNA-binding protein FXR1 · P51114 · FXR1 on Sugi Atlas →

0 patent compounds predicted against FXR1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to FXR1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Obeticholic Acid Among Chronic HBV Patients with Hepatic Steatosis : Clinical and Portal Doppler Outcomes PHASE3NOT_YET_RECRUITING
Comparative Study Between Obeticholic Acid Versus Vitamin E in Patients with Non-alcoholic Steatohepatitis PHASE2ACTIVE_NOT_RECRUITING
Cholic Acid for Hepatic Steatosis in Lipodystrophy PHASE2COMPLETED
Obeticholic Acid in Bile Acid Diarrhoea PHASE2COMPLETED
Fibrates in Pediatric Cholestasis PHASE2COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Ursodiol on Insulin Sensitivity, Gastric Emptying and Body Weight With Type 2 Diabetes on Metformin PHASE2COMPLETED
Ursodiol, Combination Chemotherapy, and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer PHASE1COMPLETED
Single Ascending Oral Dose Phase I Study With Px-102 PHASE1COMPLETED
An Open-Label Trial of Donepezil in Fragile X Syndrome PHASE1COMPLETED
Effects of FXR Activation on Hepatic Lipid and Glucose Metabolism EARLY_PHASE1COMPLETED
Role of Obeticholic Acid in the Patients of NAFLD With Raised ALT nanCOMPLETED
FGF19 in Obstructive Cholestasis: Unveil the Signal nanUNKNOWN
Mechanisms of Glucose Lowering Effect of Colesevelam HCl nanCOMPLETED
The Effect of Sleeve Gastrectomy on Post-prandial Serum Bile Acids nanCOMPLETED
Gut Microbiota and Modulation of Liver Damage in NAFLD nanCOMPLETED
The Metabolic Profile in Intrahepatic Cholestasis of Pregnancy and Diabetes Mellitus nanCOMPLETED
Effects of Colesevelam HCl On Bile Acid Kinetics nanCOMPLETED
Genetic-specific Effects of Fructose on Liver Lipogenesis nanCOMPLETED
the Role of plin5 in the Development of Nonalcoholic Fatty Liver Disease. nanUNKNOWN
Effect of SGLT2 Inhibitors on NAFLD in Type 2 Diabetic Patients with Diabetic Nephropathy nanNOT_YET_RECRUITING
Mapping Disease Pathways for Biliary Atresia nanRECRUITING
A Study to Assess Variation in Potential Biomarkers in Friedreich Ataxia nanCOMPLETED
Omics-based Predictors of NAFLD/Potential NASH nanUNKNOWN
Pediatric Evaluation and Registry for Liver Cholestasis in Canada nanRECRUITING
Genetic Analysis of Fraser Syndrome and Fryns Syndrome nanCOMPLETED
Assessing Colonic Folate Absorption & Metabolism nanUNKNOWN
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
Effect of Heavy Alcohol Consumption on Farnesoid X Receptor (FXR) Signaling nanCOMPLETED
Evaluation of MicroRNA Expression in Blood and Cytology for Detecting Barrett's Esophagus and Associated Neoplasia nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a FXR1 binder may also engage these)

ProteinNameSimilarity
Q5XI81 1.000 Q5XI81 →
O70523 1.000 O70523 →
Q2TBT7 1.000 Q2TBT7 →
Q61584 1.000 Q61584 →
P51115 1.000 P51115 →
Q7ZTQ5 1.000 Q7ZTQ5 →
Q5BJ56 1.000 Q5BJ56 →
Q6GLC9 0.999 Q6GLC9 →
F1QLR3 0.998 F1QLR3 →
Q9WVR4 0.997 Q9WVR4 →
P35922 0.996 P35922 →
Q80WE1 0.995 Q80WE1 →
Q2KHP9 0.994 Q2KHP9 →
Q06787 0.994 Q06787 →
P51113 0.994 P51113 →
Q5R9B4 0.993 Q5R9B4 →
FXR2 RNA-binding protein FXR2 0.988 landscape →
SMARCC2 SWI/SNF complex subunit SMARCC2 0.983 landscape →
Q69ZX6 0.982 Q69ZX6 →
Q9NFU0 0.982 Q9NFU0 →
Q921C3 0.981 Q921C3 →
Q8TEW0 0.981 Q8TEW0 →
Q8TDW5 0.981 Q8TDW5 →
Q5YD48 0.981 Q5YD48 →
Q812E4 0.981 Q812E4 →
A5D794 0.981 A5D794 →
Q5U4T7 0.981 Q5U4T7 →
Q3SXY8 0.980 Q3SXY8 →
Q923K9 0.980 Q923K9 →
D3Z8X7 0.979 D3Z8X7 →