SCHEMBL199007

SCHEMBL199007

CC(C)(C)OC1CCN[C@@H]1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 1/20 0.47
MEN1 O00255 1/20 0.40
BLM P54132 1/20 0.40
KMT2A Q03164 1/20 0.40
ARG1 P05089 5/20 0.37
ARG2 P78540 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5658058 1.00 SLC1A2 (0.47) SLC1A2MEN1BLMKMT2AARG1
SCHEMBL23273791 1.00 SLC1A2 (0.47) SLC1A2MEN1BLMKMT2AARG1
SCHEMBL6861146 0.82 CHRM2 (0.33) SLC1A2
SCHEMBL10680722 0.79 SLC1A2 (0.52) SLC1A2MEN1BLMKMT2AARG1
SCHEMBL7280336 0.79 SLC1A2 (0.52) SLC1A2MEN1BLMKMT2AARG1
SCHEMBL7348716 0.79 SLC1A2 (0.52) SLC1A2MEN1BLMKMT2AARG1
SCHEMBL7346916 0.79 SLC1A2 (0.52) SLC1A2MEN1BLMKMT2AARG1
Hydrochloric Acid SCHEMBL26117737 0.77 SLC1A2 (0.50) SLC1A2MEN1BLMKMT2AARG1
Hydrochloric Acid SCHEMBL202139 0.77 SLC1A2 (0.50) SLC1A2MEN1BLMKMT2AARG1
SCHEMBL6863810 0.76 SLC1A2 (0.48) SLC1A2MEN1BLMKMT2AARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088890-B2 Peptides and peptidomimetic compounds, the manufacturing thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition FIBREX MEDICAL RESEARCH & DEVELOPMENT GMBH (AT) 2012-01-03 US claimed
US-4960881-A REACTING AMINO ACID WITH ALPHA-CHLORINATED CARBONATE IN SOLVENT IN PRESENCE OF ACID SCAVENGER SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1990-10-02 US claimed
CN-116348128-A Bβ15-42 for treating viral endopdermatitis F4医药有限责任公司 2023-06-27 CN disclosed
EP-2274328-A1 PEPTIDES, PEPTIDOMIMETICS AND DERIVATIVES THEREOF, THE MANUFACTURING THEREOF AS WELL AS THEIR USE FOR PREPARING A THERAPEUTICALLY AND/OR PREVENTIVELY ACTIVE PHARMACEUTICAL COMPOSITION Fibrex Medical Research & Development GmbH (AT) 2011-01-19 EP disclosed
WO-2009137850-A1 PEPTIDES, PEPTIDOMIMETICS AND DERIVATIVES THEREOF, THE MANUFACTURING THEREOF AS WELL AS THEIR USE FOR PREPARING A THERAPEUTICALLY AND/OR PREVENTIVELY ACTIVE PHARMACEUTICAL COMPOSITION FIBREX MEDICAL RESEARCH & DEVELOPMENT GMBH (AT) 2009-11-19 WO disclosed
US-7199125-B2 Spiro-cyclic compounds useful as anti-inflammatory agents BRISTOL-MYERS SQUIBB COMPANY (US) 2007-04-03 US disclosed
US-20050119279-A1 Spiro-cyclic compounds useful as anti-inflammatory agents CEREP SA (FR) 2005-06-02 US disclosed
US-5965556-A KETO-ACID AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND METHODS FOR INHIBITING THE ACTIVITY OF SERINE PROTEASE OR THIOL PROTEASE BY ADMINISTERING THE DERIVATIVE TO A MAMMAL; ALZHEIMER'S DISEASE ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYUKAI (JP) 1999-10-12 US disclosed
US-5756763-A ENZYME INHIBITOR ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYUKAI (JP) 1998-05-26 US disclosed
EP-0709373-A1 NOVEL PYRROLIDINE DERIVATIVE ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1996-05-01 EP disclosed
US-4960881-A REACTING AMINO ACID WITH ALPHA-CHLORINATED CARBONATE IN SOLVENT IN PRESENCE OF ACID SCAVENGER SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1990-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050119279-A1 Spiro-cyclic compounds useful as anti-inflammatory agents CCR9, MSR1, CCR3 SLC1A2 4858/4885MEN1 3170/4885BLM 1802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.