SCHEMBL19901108

SCHEMBL19901108

CCN1CN(c2c(C)ccc3c2oc2ccccc23)c2ncccc21

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.35
SMN1; SMN2 Q16637 4/20 0.34
DRD4 P21917 1/20 0.34
LMNA P02545 7/20 0.33
MAPT P10636 6/20 0.33
HSD17B10 Q99714 2/20 0.32
MAPK1 P28482 3/20 0.31
KDM4E B2RXH2 2/20 0.31
HTT P42858 2/20 0.31
ALDH1A1 P00352 4/20 0.31
HRH4 Q9H3N8 3/20 0.31
THRB P10828 1/20 0.31
USP2 O75604 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MEN1 O00255 2/20 0.31
HPGD P15428 2/20 0.31
KMT2A Q03164 2/20 0.31
TP53 P04637 1/20 0.31
GRIA2 P42262 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19901136 0.92 TSHR (0.35) TSHRSMN1; SMN2DRD4LMNAMAPT
SCHEMBL20402590 0.88 PIK3CA (0.33) GRIA2
SCHEMBL19901107 0.86 TSHR (0.37) TSHRSMN1; SMN2DRD4LMNAMAPT
SCHEMBL25562857 0.84 TSHR (0.36) TSHRSMN1; SMN2DRD4LMNAMAPT
SCHEMBL24851548 0.83 TSHR (0.35) TSHRDRD4LMNAMAPTHSD17B10
SCHEMBL25562918 0.82 TSHR (0.35) TSHRDRD4LMNAMAPTHSD17B10
SCHEMBL26253480 0.82 TSHR (0.36) TSHRSMN1; SMN2DRD4LMNAMAPT
SCHEMBL19901133 0.81 TSHR (0.37) TSHRSMN1; SMN2DRD4LMNAMAPT
SCHEMBL21204226 0.78 HSD17B10 (0.35) TSHRSMN1; SMN2DRD4LMNAMAPT
SCHEMBL25514834 0.78 TSHR (0.38) TSHRSMN1; SMN2DRD4LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9905784-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-27 US disclosed