SCHEMBL25514834

SCHEMBL25514834

Cc1ccc2c(oc3ccccc32)c1N1CN(c2ccccc2)c2nccnc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
MAPT P10636 4/20 0.38
MAPK1 P28482 3/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
HSD17B10 Q99714 3/20 0.38
HTT P42858 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HCRTR1 O43613 1/20 0.38
TP53 P04637 1/20 0.38
HPGD P15428 1/20 0.38
LMNA P02545 4/20 0.35
DRD4 P21917 1/20 0.34
HRH4 Q9H3N8 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CA12 O43570 2/20 0.32
CA9 Q16790 2/20 0.32
ALDH1A1 P00352 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
PLA2G1B P04054 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25562857 0.90 TSHR (0.36) TSHRMAPTMAPK1MEN1KMT2A
SCHEMBL26253480 0.90 TSHR (0.36) TSHRMAPTMAPK1MEN1KMT2A
SCHEMBL24851637 0.87 PIK3CA (0.35) MEN1KMT2AHTTKDM4EALDH1A1
SCHEMBL22788489 0.85 TSHR (0.37) TSHRMAPTMAPK1MEN1KMT2A
SCHEMBL25562794 0.84 TSHR (0.36) TSHRMAPTMAPK1MEN1KMT2A
SCHEMBL20687032 0.83 HSD17B10 (0.35) TSHRMAPTMAPK1MEN1KMT2A
SCHEMBL23729264 0.83 TSHR (0.34) TSHRMAPTMAPK1LMNADRD4
SCHEMBL25705679 0.82 TSHR (0.41) TSHRMAPTMAPK1MEN1KMT2A
SCHEMBL19901107 0.81 TSHR (0.37) TSHRMAPTMAPK1MEN1KMT2A
SCHEMBL21204242 0.79 HSD17B10 (0.36) TSHRMAPTMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-11697662-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 US disclosed
US-11672176-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, C1R, LBR TSHR 32/4885MAPT 4481/4885MAPK1 1241/4885
US-11697662-B2 Organic electroluminescent materials and devices LIFR, C1R, LBR TSHR 28/4885MAPT 4517/4885MAPK1 1045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.