SCHEMBL19901549

SCHEMBL19901549

CCc1cn(C(C)[SiH3])nn1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 12/20 0.44
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7651892 0.83 CYP19A1 (0.42) CYP19A1POLB
SCHEMBL24974351 0.80 CYP19A1 (0.40) CYP19A1POLB
SCHEMBL20926022 0.80 CYP19A1 (0.40) CYP19A1POLB
SCHEMBL18378631 0.77 CYP19A1 (0.38) CYP19A1POLB
SCHEMBL19986373 0.74 CYP19A1 (0.40) CYP19A1POLB
SCHEMBL16216100 0.72 CYP19A1 (0.60) CYP19A1
SCHEMBL19419498 0.72 CYP19A1 (0.37) CYP19A1POLB
SCHEMBL20272644 0.71
SCHEMBL15944060 0.69 CYP19A1 (0.55) CYP19A1
SCHEMBL19705751 0.68 CYP19A1 (0.61) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9901647-B2 Conjugates comprising cell-binding agents and cytotoxic agents IMMUNOGEN, INC. (US) 2018-02-27 US disclosed