Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19901700 | 0.97 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DSMPD1 | |
| SCHEMBL19901690 | 0.96 | SMPD1 (0.48) | PDE4APDE4BPDE4CPDE4DSMPD1 | |
| SCHEMBL19901676 | 0.93 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DSMPD1 | |
| SCHEMBL21281440 | 0.90 | MARS1 (0.43) | PDE4APDE4BPDE4CPDE4DTP53 | |
| SCHEMBL20857162 | 0.88 | SCD (0.38) | PDE4DSMPD1POLBNPC1RAB9A | |
| SCHEMBL620900 | 0.87 | SCD (0.39) | PDE4DSMPD1POLBNPC1RAB9A | |
| SCHEMBL618508 | 0.87 | POLB (0.41) | PDE4DSMPD1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL621642 | 0.87 | POLB (0.41) | PDE4DSMPD1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL20857173 | 0.85 | MAPT (0.37) | POLBNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL21281165 | 0.84 | MCHR1 (0.44) | POLBNPC1RAB9AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902737-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2018-02-27 | — | — | US | disclosed |