Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 14/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22383489 | 0.88 | GBA1 (0.42) | GBA1HCRTR1HCRTR2 | |
| SCHEMBL19894036 | 0.85 | HCRTR1 (0.41) | GBA1HCRTR1HCRTR2 | |
| SCHEMBL19894035 | 0.81 | HCRTR1 (0.45) | HCRTR1HCRTR2 | |
| SCHEMBL19894101 | 0.77 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL19893864 | 0.77 | GBA1 (0.37) | GBA1HCRTR1HCRTR2 | |
| SCHEMBL22383506 | 0.75 | HSD17B10 (0.53) | GBA1HCRTR1HCRTR2 | |
| SCHEMBL19894018 | 0.75 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL19893943 | 0.74 | HSD17B10 (0.42) | GBA1HCRTR1HCRTR2 | |
| SCHEMBL22383442 | 0.74 | HCRTR1 (0.70) | GBA1HCRTR1HCRTR2 | |
| SCHEMBL20212709 | 0.72 | HCRTR1 (0.48) | GBA1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287454-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-28 | — | — | EP | disclosed |