Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718053 | 0.84 | LMNA (0.48) | LMNAL3MBTL1TDP1KDM4EUSP2 | |
| SCHEMBL19419877 | 0.77 | LMNA (0.42) | LMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL6847774 | 0.77 | LMNA (0.42) | LMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL3403121 | 0.77 | LMNA (0.42) | LMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL8743382 | 0.74 | LMNA (0.40) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL8431961 | 0.74 | LMNA (0.40) | LMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL5873459 | 0.74 | LMNA (0.40) | LMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL27837830 | 0.74 | LMNA (0.31) | LMNAL3MBTL1 | |
| SCHEMBL17468058 | 0.72 | LMNA (0.38) | LMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL18285214 | 0.72 | LMNA (0.46) | LMNAL3MBTL1TDP1KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512446-A1 | COMPOSITION OF DEXIBUPROFEN TRANSDERMAL HYDROGEL | Shasun Pharmaceuticals Limited (IN) | 2012-10-24 | — | — | EP | disclosed |
| CN-102665681-A | Composition of dexibuprofen transdermal hydrogel | SHASUN PHARMACEUTICALS LTD | 2012-09-12 | — | — | CN | disclosed |
| WO-2011073998-A1 | COMPOSITION OF DEXIBUPROFEN TRANSDERMAL HYDROGEL | SHASUN PHARMACEUTICALS LIMITED (IN) | 2011-06-23 | — | — | WO | disclosed |
| US-20080096784-A1 | Composition for Cleaning Dental Instruments and Process | VOCO GMBH (DE) | 2008-04-24 | — | — | US | disclosed |