Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 4/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990350 | 1.00 | PTGER1 (0.51) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL1995519 | 0.93 | KMT2A (0.45) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL1989522 | 0.90 | PTGER1 (0.46) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL1989523 | 0.90 | PTGER1 (0.46) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL12121776 | 0.89 | PTGER1 (0.46) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL4832151 | 0.89 | GAA (0.48) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL2887009 | 0.86 | PTGER1 (0.43) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL12986736 | 0.86 | KMT2A (0.47) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL13257883 | 0.86 | KMT2A (0.47) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL1991102 | 0.85 | KMT2A (0.43) | PTGER1PTGER4PTGER3PTGER2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152227-A1 | DEUTERIUM LABELLED DERIVATIVES OF 3-(2-HYDROXY-5-METHYPHENYL)-N,N-DIISOPROPYL-3-PHENYLPROPYLAMINE AND METHODS OF USE THEREOF | CONCERT PHARMACEUTICALS INC. (US) | 2011-06-23 | — | — | US | disclosed |
| US-20110152227-A1 | DEUTERIUM LABELLED DERIVATIVES OF 3-(2-HYDROXY-5-METHYPHENYL)-N,N-DIISOPROPYL-3-PHENYLPROPYLAMINE AND METHODS OF USE THEREOF | CONCERT PHARMACEUTICALS INC. (US) | 2011-06-23 | — | — | US | disclosed |
| WO-2010092500-A2 | A PROCESS FOR THE PREPARATION OF TOLTERODINE TARTRATE | ALEMBIC LIMITED (IN) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010046801-A2 | A PROCESS FOR THE PREPARATION OF TOLTERODINE TARTRATE | ALEMBIC LIMITED (IN) | 2010-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152227-A1 | DEUTERIUM LABELLED DERIVATIVES OF 3-(2-HYDROXY-5-METHYPHENYL)-N,N-DIISOPROPYL-3-PHENYLPROPYLAMINE AND METHODS OF USE THEREOF | ADRB3, CHRM3, QDPR | PTGER1 728/4885PTGER4 457/4885PTGER3 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.