Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 4/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | BCHE | P06276 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ELAVL3 | Q14576 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19903744 | 0.93 | SERPINE1 (0.63) | SERPINE1PTPN1BCHEKDM4EPOLB | |
| SCHEMBL19903731 | 0.86 | SERPINE1 (0.55) | SERPINE1PTPN1BCHEKDM4ETDP1 | |
| SCHEMBL19903720 | 0.86 | SERPINE1 (0.55) | SERPINE1PTPN1BCHEKDM4ETDP1 | |
| SCHEMBL12702927 | 0.81 | PTPN1 (0.59) | SERPINE1PTPN1BCHEKDM4ELMNA | |
| SCHEMBL19903734 | 0.80 | BCHE (0.49) | SERPINE1PTPN1BCHEXDHPRKCA | |
| SCHEMBL12258554 | 0.78 | BCHE (0.56) | PTPN1BCHELMNA | |
| SCHEMBL12258550 | 0.78 | BCHE (0.56) | PTPN1BCHELMNA | |
| SCHEMBL19903648 | 0.78 | BCHE (0.53) | SERPINE1PTPN1BCHEDYRK1AIGF1R | |
| SCHEMBL5665815 | 0.75 | PTPN1 (0.82) | SERPINE1PTPN1L3MBTL1DYRK1APRKD3 | |
| SCHEMBL2225426 | 0.75 | PTPN1 (0.82) | SERPINE1PTPN1L3MBTL1DYRK1APRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287462-A1 | ISOSORBIDE DERIVATIVES TO TREAT BACTERIAL BIOFILMS | NITTO DENKO CORPORATION (JP) | 2018-02-28 | — | — | EP | disclosed |