Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 4/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | PRKCB | P05771 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | PRKCH | P24723 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.47 |
| ▸ | MET | P08581 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19903721 | 0.93 | SERPINE1 (0.55) | SERPINE1PTPN1BCHEDYRK1APRKD3 | |
| SCHEMBL19903731 | 0.93 | SERPINE1 (0.55) | SERPINE1PTPN1BCHEDYRK1APRKD3 | |
| SCHEMBL19903720 | 0.93 | SERPINE1 (0.55) | SERPINE1PTPN1BCHEDYRK1APRKD3 | |
| SCHEMBL19903648 | 0.84 | BCHE (0.53) | SERPINE1PTPN1BCHEDYRK1AIGF1R | |
| SCHEMBL19903734 | 0.83 | BCHE (0.49) | SERPINE1PTPN1BCHEPRKCA | |
| SCHEMBL12702927 | 0.81 | PTPN1 (0.59) | SERPINE1PTPN1BCHEDYRK1AKDM4E | |
| SCHEMBL2225426 | 0.81 | PTPN1 (0.82) | SERPINE1PTPN1DYRK1APRKD3PRKCG | |
| SCHEMBL5665815 | 0.81 | PTPN1 (0.82) | SERPINE1PTPN1DYRK1APRKD3PRKCG | |
| SCHEMBL5908763 | 0.81 | PTPN1 (0.82) | SERPINE1PTPN1DYRK1APRKD3PRKCG | |
| SCHEMBL3654334 | 0.80 | SERPINE1 (0.86) | SERPINE1PTPN1DYRK1APRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287462-A1 | ISOSORBIDE DERIVATIVES TO TREAT BACTERIAL BIOFILMS | NITTO DENKO CORPORATION (JP) | 2018-02-28 | — | — | EP | disclosed |