Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.33 |
| ▸ | GLP1R | P43220 | 8/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919167 | 1.00 | PLK1 (0.40) | PLK1AKT1TLR2TLR1P2RY12 | |
| SCHEMBL24175784 | 0.93 | AKT1 (0.40) | PLK1AKT1TLR2TLR1P2RY12 | |
| SCHEMBL16273727 | 0.88 | AKT1 (0.41) | PLK1AKT1P2RY12TDP1 | |
| SCHEMBL15919172 | 0.88 | AKT1 (0.41) | PLK1AKT1P2RY12TDP1 | |
| SCHEMBL31648515 | 0.86 | MGLL (0.41) | PLK1AKT1TLR2TLR1MGLL | |
| SCHEMBL16329598 | 0.86 | GLP1R (0.45) | PLK1AKT1TLR2TLR1GLP1R | |
| SCHEMBL19541913 | 0.86 | GLP1R (0.45) | PLK1AKT1TLR2TLR1GLP1R | |
| SCHEMBL22025537 | 0.86 | GLP1R (0.45) | PLK1AKT1TLR2TLR1GLP1R | |
| SCHEMBL16329597 | 0.86 | GLP1R (0.45) | PLK1AKT1TLR2TLR1GLP1R | |
| SCHEMBL26445412 | 0.86 | GLP1R (0.45) | PLK1AKT1TLR2TLR1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2949665-B1 | GLYCOSYLATION ATRIAL NATRIURETIC PEPTIDE | DAIICHI SANKYO CO LTD (JP) | 2018-02-28 | — | — | EP | disclosed |