Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 6/20 | 0.61 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | HBB | P68871 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10104166 | 0.94 | KDM4A (0.63) | KDM4AKDM2AMEN1KMT2AMAPT | |
| Bromide SCHEMBL339322 | 0.92 | KDM4A (0.61) | KDM4AKDM2AMEN1KMT2AMAPT | |
| Bromide SCHEMBL339321 | 0.92 | KDM4A (0.61) | KDM4AKDM2AMEN1KMT2AMAPT | |
| SCHEMBL10313125 | 0.89 | KDM4A (0.56) | KDM4AKDM2AMEN1KMT2AMAPT | |
| SCHEMBL12201183 | 0.87 | KDM4A (0.58) | KDM4AKDM2AMEN1KMT2AMAPT | |
| SCHEMBL19649090 | 0.83 | KDM4A (0.61) | KDM4AKDM2AMEN1KMT2AMAPT | |
| SCHEMBL10104442 | 0.82 | KDM4A (0.74) | KDM4AKDM2AMEN1KMT2AMAPT | |
| SCHEMBL10104197 | 0.82 | KDM4A (0.74) | KDM4AKDM2AMEN1KMT2AMAPT | |
| SCHEMBL14984144 | 0.82 | KDM4A (0.73) | KDM4AKDM2AMEN1KMT2AMAPT | |
| SCHEMBL10104220 | 0.82 | KDM4A (0.50) | KDM4AKDM2AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651374-B1 | PROCESS FOR DYEING KERATIN FIBRES USING A DIRECT DYE BEARING A DISULFIDE/THIOL/PROTECTED THIOL FUNCTION AND WATER VAPOUR | L'ORÉAL (FR) | 2018-02-28 | — | — | EP | disclosed |