Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23787842 | 0.81 | HSD17B3 (0.49) | HSD17B3APPCRHBPCRHR2TLR9 | |
| SCHEMBL12451468 | 0.78 | KDM4A (0.43) | HSD17B3APPCRHBPCRHR2TLR9 | |
| SCHEMBL17081896 | 0.76 | HSD17B3 (0.43) | HSD17B3APPCRHBPCRHR2TLR9 | |
| SCHEMBL19003857 | 0.75 | NPC1 (0.30) | NPC1 | |
| SCHEMBL16997447 | 0.73 | — | — | |
| SCHEMBL19649060 | 0.73 | CYP3A4 (0.33) | APPBACE1 | |
| SCHEMBL23787807 | 0.71 | KDM4A (0.33) | TLR9MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL14986920 | 0.69 | KDM4A (0.54) | HSD17B3APPCRHBPCRHR2TLR9 | |
| SCHEMBL14986873 | 0.67 | HSD17B3 (0.51) | HSD17B3APPCRHBPCRHR2TLR9 | |
| SCHEMBL7655430 | 0.66 | HSD17B3 (0.79) | HSD17B3APPCRHBPCRHR2TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651374-B1 | PROCESS FOR DYEING KERATIN FIBRES USING A DIRECT DYE BEARING A DISULFIDE/THIOL/PROTECTED THIOL FUNCTION AND WATER VAPOUR | L'ORÉAL (FR) | 2018-02-28 | — | — | EP | disclosed |