Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14986920 | 0.90 | KDM4A (0.54) | HSD17B3APPCRHBPCRHR2TLR9 | |
| SCHEMBL17081833 | 0.86 | ALDH1A1 (0.41) | TLR9MAPTMEN1NPC1MAPK1 | |
| SCHEMBL14986919 | 0.79 | CHRM2 (0.47) | APPTLR9MAPTKDM4AKDM2A | |
| SCHEMBL14986927 | 0.78 | CHRM2 (0.48) | APPTLR9MAPTKDM4AKDM2A | |
| SCHEMBL14986873 | 0.76 | HSD17B3 (0.51) | HSD17B3APPCRHBPCRHR2TLR9 | |
| SCHEMBL19903948 | 0.76 | HSD17B3 (0.42) | HSD17B3APPCRHBPCRHR2TLR9 | |
| SCHEMBL17231187 | 0.74 | APP (0.37) | HSD17B3APPCRHBPCRHR2TLR9 | |
| SCHEMBL19663850 | 0.72 | HTT (0.39) | MAPTKDM4AKDM2AMEN1NPC1 | |
| SCHEMBL15251115 | 0.71 | ALDH1A1 (0.36) | TLR9MAPTMEN1NPC1MAPK1 | |
| SCHEMBL16310052 | 0.71 | ALDH1A1 (0.44) | TLR9MAPTMEN1NPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160280921-A1 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION | ENZO LIFE SCIENCES, INC. (US) | 2016-09-29 | — | — | US | disclosed |
| US-20150376411-A1 | NOVEL DYES AND COMPOSITIONS, AND PROCESSES FOR USING SAME IN ANALYSIS OF PROTEIN AGGREGATION AND OTHER APPLICATIONS | ENZO BIOCHEM, INC. (US) | 2015-12-31 | — | — | US | disclosed |
| US-9133343-B2 | Dyes and compositions, and processes for using same in analysis of protein aggregation and other applications | ENZO BIOCHEM, INC. (US) | 2015-09-15 | — | — | US | disclosed |