Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 8/20 | 0.37 |
| ▸ | PGR | P06401 | 7/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172998 | 0.84 | IDO1 (0.46) | NR3C1CHRM3IDO1ACHE | |
| SCHEMBL10170297 | 0.84 | NR3C1 (0.40) | NR3C1CHRM3NR3C2PGRCYP3A4 | |
| SCHEMBL29561309 | 0.84 | IDO1 (0.46) | NR3C1CHRM3IDO1ACHE | |
| SCHEMBL14488897 | 0.80 | NR3C1 (0.38) | NR3C1CHRM3NR3C2PGRCYP3A4 | |
| SCHEMBL18711606 | 0.80 | NR3C1 (0.44) | NR3C1CHRM3NR3C2PGRCYP3A4 | |
| SCHEMBL23029423 | 0.79 | SMN1; SMN2 (0.42) | CYP3A4ACHE | |
| SCHEMBL22900080 | 0.76 | TSHR (0.41) | ACHE | |
| SCHEMBL29519382 | 0.76 | NR3C1 (0.36) | NR3C1NR3C2IDO1 | |
| SCHEMBL19693724 | 0.76 | NR3C1 (0.36) | NR3C1NR3C2IDO1 | |
| SCHEMBL5644409 | 0.75 | NR3C1 (0.36) | NR3C1CHRM3NR3C2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958907-B1 | BENZOTHIOPHENE DERIVATIVES AND COMPOSITIONS THEREOF AS SELECTIVE ESTROGEN RECEPTOR DEGRADERS | NOVARTIS AG (CH) | 2018-02-28 | — | — | EP | disclosed |