Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14455123 | 0.91 | CYP1A2 (0.59) | TSHRDGKAPAMCYP1A2ALDH1A1 | |
| SCHEMBL29160902 | 0.91 | DGKA (0.65) | TSHRDGKAPAMMAPTALDH1A1 | |
| SCHEMBL9741789 | 0.89 | DGKA (0.69) | TSHRDGKAPAMMAPTALDH1A1 | |
| SCHEMBL6602446 | 0.89 | DGKA (0.47) | TSHRDGKAPAMMAPTALDH1A1 | |
| SCHEMBL22521636 | 0.89 | DGKA (0.69) | TSHRDGKAPAMMAPTALDH1A1 | |
| SCHEMBL24609200 | 0.89 | DGKA (0.69) | TSHRDGKAPAMMAPTALDH1A1 | |
| SCHEMBL11965460 | 0.89 | DGKA (0.47) | TSHRDGKAPAMMAPTALDH1A1 | |
| SCHEMBL20751620 | 0.89 | DGKA (0.69) | TSHRDGKAPAMMAPTALDH1A1 | |
| SCHEMBL28395913 | 0.88 | TSHR (0.53) | TSHRDGKAPAMCYP1A2MAPT | |
| SCHEMBL881356 | 0.87 | DGKA (0.56) | TSHRDGKAPAMCYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791258-B2 | Pro-fluorescent probes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-07-29 | — | — | US | disclosed |
| US-20110130306-A1 | PRO-FLUORESCENT PROBES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-02 | — | — | US | disclosed |
| WO-2009152102-A2 | PRO-FLUORESCENT PROBES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130306-A1 | PRO-FLUORESCENT PROBES | PRDX5, FIS1, PRDX3 | TSHR 2920/4885DGKA 3910/4885PAM 207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.