Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987448 | 0.88 | — | — | |
| SCHEMBL2156256 | 0.88 | — | — | |
| SCHEMBL3562819 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL22979118 | 0.86 | SMYD3 (0.47) | SMYD3XIAPKMT2ALMNABLM | |
| Hydrochloric Acid SCHEMBL22979117 | 0.86 | SMYD3 (0.47) | SMYD3XIAPKMT2ALMNABLM | |
| SCHEMBL3401698 | 0.85 | SMYD3 (0.41) | SMYD3MMETSHRKMT2ASMN1; SMN2 | |
| SCHEMBL22629584 | 0.81 | EPHX1 (0.50) | SMYD3XIAPKMT2ALMNABLM | |
| SCHEMBL15906217 | 0.81 | EPHX1 (0.50) | SMYD3XIAPKMT2ALMNABLM | |
| SCHEMBL13457996 | 0.81 | EPHX2 (0.54) | SMYD3TSHRXIAPKMT2ALMNA | |
| SCHEMBL15906216 | 0.81 | EPHX1 (0.50) | SMYD3XIAPKMT2ALMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2684880-B1 | DISPIROPYRROLIDINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2018-02-28 | — | — | EP | disclosed |