Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | WNT1 | P04628 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20030734 | 0.93 | KDM4E (0.36) | KDM4EKMT2AMEN1ALDH1A1WNT1 | |
| SCHEMBL19905929 | 0.90 | EIF4EBP1 (0.32) | KDM4EKMT2AMEN1ALDH1A1PTGDR2 | |
| SCHEMBL15342591 | 0.84 | PSIP1 (0.35) | — | |
| SCHEMBL22506340 | 0.84 | PSIP1 (0.35) | — | |
| SCHEMBL19906158 | 0.84 | KDM4E (0.34) | KDM4EKMT2AMEN1ALDH1A1PTGDR2 | |
| SCHEMBL19905785 | 0.84 | KDM4E (0.38) | KDM4EKMT2AMEN1ALDH1A1PTGDR2 | |
| SCHEMBL20030685 | 0.83 | KDM4E (0.33) | KDM4EKMT2AMEN1ALDH1A1PTGDR2 | |
| SCHEMBL31114857 | 0.83 | CNR1 (0.31) | — | |
| SCHEMBL20101206 | 0.83 | CNR1 (0.31) | — | |
| SCHEMBL19906364 | 0.83 | KDM4E (0.36) | KDM4EKMT2AMEN1ALDH1A1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |