PSIP1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL99991	0.61	4/20
SCHEMBL99100	0.59	4/20
SCHEMBL99359	0.48	3/20
SCHEMBL180713	1.00	2/20
SCHEMBL506696	1.00	2/20
SCHEMBL789569	0.82	2/20
SCHEMBL293991	0.74	2/20
SCHEMBL709880	0.63	2/20
SCHEMBL710799	0.63	2/20
SCHEMBL86088	0.61	2/20
SCHEMBL99423	0.60	2/20
SCHEMBL5375	0.58	2/20
Fluoresone (SCHEMBL24999)	0.58	2/20
SCHEMBL159760	0.58	2/20
SCHEMBL198600	0.58	2/20
SCHEMBL248212	0.58	2/20
SCHEMBL165384	0.57	2/20
SCHEMBL461875	0.56	2/20
SCHEMBL462642	0.56	2/20
SCHEMBL99072	0.56	2/20

Clinical trials — most relevant to PSIP1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
The Effect of the Preoperative Oral Carbohydrate Attenuating Immediate Postoperative Insulin Resistance on PI3K Dependent Signaling Pathway	PHASE4	COMPLETED
Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety	PHASE2	COMPLETED
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients	PHASE2	COMPLETED
Study of Sorafenib and Docetaxel in Metastatic Prostate Cancer	PHASE2	COMPLETED
Systemic Therapy and Chemoradiation in Advanced Localised Pancreatic Cancer - 2	PHASE1/PHASE2	COMPLETED
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)	PHASE1/PHASE2	RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis	nan	COMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia	nan	NOT_YET_RECRUITING
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia	nan	UNKNOWN
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact	nan	UNKNOWN
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Biomarkers in Idiopathic Juvenile Arthritis	nan	UNKNOWN
Gut Microbiome in Patients With Polycystic Ovary Syndrome	nan	UNKNOWN
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients	nan	RECRUITING
Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study	nan	RECRUITING
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED
Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF)	nan	UNKNOWN
Dried Fruit and Postprandial Glycemia Trial	nan	UNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population	nan	COMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Genetic Investigation of Solid Tumors Cohort	nan	COMPLETED
Germline Mutations in Pancreatic Adenocarcinoma	nan	COMPLETED
Markers for Early Detection of Prostate Cancer	nan	COMPLETED
A Prospective, Single-centre，Single-blinded Study of PROUD for Prostate Carcinoma Diagnosis	nan	UNKNOWN
Diagnosis of Primary Ciliary Dyskinesia	nan	COMPLETED
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis	nan	UNKNOWN
Study of Neurodegenerative Diseases Induced Stem Cells in Patients and Healthy Family Controls.	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a PSIP1 binder may also engage these)

Protein	Name	Similarity
Q66T72	—	1.000	Q66T72 →
Q99JF8	—	1.000	Q99JF8 →
Q8MJG1	—	1.000	Q8MJG1 →
Q812D1	—	1.000	Q812D1 →
Q5XXA9	—	0.999	Q5XXA9 →
Q9JMG7	—	0.989	Q9JMG7 →
Q923W4	—	0.988	Q923W4 →
Q6P4K1	—	0.986	Q6P4K1 →
Q32N87	—	0.986	Q32N87 →
F8VPQ2	—	0.985	F8VPQ2 →
Q9JKB5	—	0.985	Q9JKB5 →
Q8CCG4	—	0.984	Q8CCG4 →
Q2TB10	—	0.984	Q2TB10 →
Q5XXA7	—	0.984	Q5XXA7 →
Q62315	—	0.984	Q62315 →
Q0VEE6	—	0.984	Q0VEE6 →
NSD3	Histone-lysine N-methyltransferase NSD3	0.983	landscape →
Q9BTC0	—	0.983	Q9BTC0 →
PHF20	PHD finger protein 20	0.983	landscape →
Q4LE39	—	0.982	Q4LE39 →
A8MW92	—	0.982	A8MW92 →
Q5F363	—	0.982	Q5F363 →
P51859	—	0.982	P51859 →
Q6ZSZ6	—	0.982	Q6ZSZ6 →
SMARCC2	SWI/SNF complex subunit SMARCC2	0.982	landscape →
Q8R515	—	0.982	Q8R515 →
HDGFL3	Hepatoma-derived growth factor-related protein 3	0.982	landscape →
Q9FLU1	—	0.981	Q9FLU1 →
Q5VWG9	—	0.981	Q5VWG9 →
Q8C0C0	—	0.981	Q8C0C0 →