Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | LIPC | P11150 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19905831 | 0.90 | PIK3CD (0.42) | KDM4EPTGDR2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL19905796 | 0.89 | KDM4E (0.39) | KDM4EPTGDR2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL19905882 | 0.88 | KDM4E (0.41) | KDM4EPTGDR2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL19906018 | 0.88 | KDM4E (0.35) | KDM4ES1PR1LIPCPTGDR2ALDH1A1 | |
| SCHEMBL17547146 | 0.85 | KDM4E (0.39) | KDM4EPTGDR2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL15341113 | 0.84 | CYP3A4 (0.37) | S1PR1LIPC | |
| SCHEMBL17547045 | 0.83 | KDM4E (0.37) | KDM4EPTGDR2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL15341043 | 0.82 | LIPC (0.36) | S1PR1LIPCPFKFB3NAMPTPRMT5 | |
| SCHEMBL19906088 | 0.81 | KDM4E (0.42) | KDM4EPTGDR2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL19905803 | 0.81 | KDM4E (0.39) | KDM4EPTGDR2ALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |