Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15341098 | 1.00 | CYP3A4 (0.39) | CYP3A4PSIP1MAP4K4 | |
| SCHEMBL15340988 | 0.94 | CYP3A4 (0.33) | CYP3A4MAP4K4 | |
| SCHEMBL15342613 | 0.92 | CYP3A4 (0.38) | CYP3A4PSIP1 | |
| SCHEMBL15342614 | 0.91 | CYP3A4 (0.38) | CYP3A4PSIP1 | |
| SCHEMBL15341103 | 0.89 | CYP3A4 (0.39) | CYP3A4PSIP1 | |
| SCHEMBL15341107 | 0.89 | CYP3A4 (0.40) | CYP3A4PSIP1 | |
| SCHEMBL15342558 | 0.89 | CYP3A4 (0.37) | CYP3A4PSIP1 | |
| SCHEMBL15341114 | 0.88 | CYP3A4 (0.38) | CYP3A4PSIP1MAP4K4 | |
| SCHEMBL19905770 | 0.88 | CYP3A4 (0.38) | CYP3A4PSIP1MAP4K4 | |
| SCHEMBL15341120 | 0.88 | CYP3A4 (0.38) | CYP3A4PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |