Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 7/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.32 |
| ▸ | PPARD | Q03181 | 4/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906072 | 0.91 | KDM4E (0.34) | KDM4ESMN1; SMN2LMNAF11KLKB1 | |
| SCHEMBL19906039 | 0.88 | PPARD (0.33) | KDM4ESMN1; SMN2LMNAPPARDPPARG | |
| SCHEMBL19906161 | 0.88 | KDM4E (0.35) | KDM4ESMN1; SMN2LMNAPPARDPTGDR2 | |
| SCHEMBL19906172 | 0.87 | LMNA (0.38) | KDM4ESMN1; SMN2LMNAF11KLKB1 | |
| SCHEMBL19905888 | 0.86 | KDM4E (0.35) | KDM4ESMN1; SMN2LMNAF11KLKB1 | |
| SCHEMBL19906352 | 0.85 | PTGDR2 (0.36) | KDM4ESMN1; SMN2LMNAPTGDR2MEN1 | |
| SCHEMBL19906166 | 0.85 | KDM4E (0.40) | KDM4ESMN1; SMN2LMNAPTGDR2MEN1 | |
| SCHEMBL19906314 | 0.83 | KDM4E (0.40) | KDM4ESMN1; SMN2LMNAPTGDR2MEN1 | |
| SCHEMBL19906391 | 0.81 | KDM4E (0.33) | KDM4ESMN1; SMN2LMNAPPARDPTGDR2 | |
| SCHEMBL19905880 | 0.81 | KDM4E (0.38) | KDM4ESMN1; SMN2LMNAPTGDR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |