Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19905960 | 0.87 | KDM4E (0.42) | PTGDR2KDM4EAKR1B1 | |
| SCHEMBL15331864 | 0.83 | CYP3A4 (0.40) | PTGDR2AKR1B1 | |
| SCHEMBL15333590 | 0.83 | CYP3A4 (0.40) | PTGDR2AKR1B1 | |
| SCHEMBL19906186 | 0.82 | KDM4E (0.42) | PTGDR2KDM4ESLC22A12 | |
| SCHEMBL15342118 | 0.82 | SLC16A3 (0.35) | PTGDR2KDM4EAKR1B1SLC22A12 | |
| SCHEMBL19906076 | 0.81 | KDM4E (0.37) | PTGDR2KDM4EAKR1B1 | |
| SCHEMBL15342532 | 0.81 | F2RL3 (0.36) | PTGDR2KDM4EAKR1B1 | |
| SCHEMBL19905855 | 0.81 | KDM4E (0.39) | PTGDR2KDM4EAKR1B1 | |
| SCHEMBL19906165 | 0.80 | KDM4E (0.40) | PTGDR2KDM4EAKR1B1 | |
| SCHEMBL19905953 | 0.79 | KDM4E (0.42) | PTGDR2KDM4EAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |