Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 10/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19905844 | 0.90 | PTGDR2 (0.35) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19905882 | 0.87 | KDM4E (0.41) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906288 | 0.87 | CSF1R (0.35) | KDRFGFR3KDM4EPTGDR2MEN1 | |
| SCHEMBL19906178 | 0.87 | PTGDR2 (0.35) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL17547144 | 0.87 | PTGDR2 (0.35) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19905859 | 0.86 | PTGDR2 (0.37) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL17547166 | 0.86 | PTGDR2 (0.38) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906317 | 0.86 | PTGDR2 (0.35) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19905848 | 0.85 | KDM4E (0.36) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906377 | 0.85 | PTGDR2 (0.39) | KDM4EPTGDR2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |