Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 7/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 6/20 | 0.34 |
| ▸ | MET | P08581 | 3/20 | 0.34 |
| ▸ | FLT3 | P36888 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19905880 | 0.89 | KDM4E (0.38) | CSF1RMETFLT3KDM4EMEN1 | |
| SCHEMBL19906069 | 0.89 | EGFR (0.35) | EGFRKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906126 | 0.88 | KDM4E (0.33) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906320 | 0.88 | KDM4E (0.31) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906072 | 0.87 | KDM4E (0.34) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906287 | 0.87 | KDR (0.37) | CSF1RKDRFGFR3EGFRKDM4E | |
| SCHEMBL19906229 | 0.87 | EIF4E (0.36) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19905857 | 0.87 | HRH4 (0.34) | KDM4E | |
| SCHEMBL19906122 | 0.87 | KDM4C (0.34) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906017 | 0.87 | KDM4E (0.32) | KDM4EMEN1ALDH1A1KMT2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |