Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.33 |
| ▸ | RRM1 | P23921 | 6/20 | 0.33 |
| ▸ | RRM2B | Q7LG56 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20132605 | 0.81 | MAP3K14 (0.36) | MAP3K14CHRM2CHRM1RRM1RRM2B | |
| SCHEMBL3267534 | 0.79 | MAP3K14 (0.53) | MAP3K14CHRM2CHRM1RRM1RRM2B | |
| SCHEMBL3267103 | 0.77 | MAP3K14 (0.44) | MAP3K14CHRM2CHRM1RRM1RRM2B | |
| SCHEMBL21752405 | 0.71 | MAP3K14 (0.40) | MAP3K14CHRM2CHRM1RRM1RRM2B | |
| SCHEMBL8400852 | 0.71 | MAP3K14 (0.41) | MAP3K14 | |
| SCHEMBL28892296 | 0.70 | MAP3K14 (0.33) | MAP3K14 | |
| SCHEMBL30829732 | 0.70 | MAP3K14 (0.33) | MAP3K14 | |
| SCHEMBL25352751 | 0.69 | MAP3K14 (0.40) | MAP3K14 | |
| SCHEMBL22143751 | 0.69 | MAP3K14 (0.40) | MAP3K14 | |
| SCHEMBL27376978 | 0.68 | HTR2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |