Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25352751 | 1.00 | MAP3K14 (0.40) | MAP3K14HTR1APARP1ADRA2AP2RX7 | |
| SCHEMBL31357918 | 0.81 | — | — | |
| SCHEMBL1266174 | 0.79 | KDM1A (0.33) | PARP1ADRA2A | |
| SCHEMBL25351934 | 0.79 | ADRA2A (0.32) | ADRA2A | |
| SCHEMBL22143867 | 0.79 | PGR (0.33) | ADRA2A | |
| SCHEMBL24593733 | 0.79 | PGR (0.33) | ADRA2A | |
| SCHEMBL12926173 | 0.79 | KDM1A (0.33) | PARP1ADRA2A | |
| SCHEMBL3988257 | 0.79 | KDM1A (0.33) | PARP1ADRA2A | |
| Hydrochloric Acid SCHEMBL1265324 | 0.77 | KDM1A (0.33) | PARP1ADRA2A | |
| SCHEMBL22143945 | 0.75 | ADRA2A (0.50) | MAP3K14HTR1AADRA2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11377425-B1 | Small molecule modulators of IL-17 | LEO PHARMA A/S (DK) | 2022-07-05 | — | — | US | disclosed |
| WO-2020127685-A1 | AMINO-ACID ANILIDES AS SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11377425-B1 | Small molecule modulators of IL-17 | IL17A, IL15, IL2 | MAP3K14 707/4885HTR1A 3046/4885PARP1 4301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.