Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.69 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906636 | 0.82 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL22420510 | 0.82 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL20107103 | 0.82 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL20107102 | 0.77 | P2RX7 (0.73) | P2RX7MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL20107015 | 0.76 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL19907147 | 0.76 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL19907049 | 0.76 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL22420530 | 0.75 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL19906678 | 0.71 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL22420578 | 0.69 | P2RX7 (1.00) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287443-A1 | 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Shionogi & Co., Ltd (JP) | 2018-02-28 | — | — | EP | disclosed |