SCHEMBL19906745

SCHEMBL19906745

Cc1ccccc1Nc1nc(=O)c(C(=O)N(C)C)cn1Cc1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 20/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19906740 0.88 P2RX7 (1.00) P2RX7
SCHEMBL22420560 0.81 P2RX7 (1.00) P2RX7
SCHEMBL19906542 0.78 P2RX7 (1.00) P2RX7
SCHEMBL19906696 0.78 P2RX7 (1.00) P2RX7
SCHEMBL19906714 0.77 P2RX7 (1.00) P2RX7
SCHEMBL19906642 0.77 P2RX7 (1.00) P2RX7
SCHEMBL19906471 0.77 P2RX7 (1.00) P2RX7
SCHEMBL19907245 0.74 P2RX7 (1.00) P2RX7
SCHEMBL19907403 0.74 P2RX7 (1.00) P2RX7
SCHEMBL19906593 0.73 P2RX7 (1.00) P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3287443-A1 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Shionogi & Co., Ltd (JP) 2018-02-28 EP disclosed