Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20107081 | 0.89 | P2RX7 (0.63) | P2RX7 | |
| SCHEMBL20107043 | 0.89 | P2RX7 (0.65) | P2RX7 | |
| SCHEMBL20107083 | 0.85 | P2RX7 (0.62) | P2RX7 | |
| SCHEMBL20107079 | 0.85 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL20106958 | 0.82 | P2RX7 (0.62) | P2RX7 | |
| SCHEMBL19906848 | 0.78 | P2RX7 (0.82) | P2RX7 | |
| SCHEMBL20107097 | 0.78 | P2RX7 (0.61) | P2RX7 | |
| SCHEMBL20106974 | 0.75 | P2RX7 (0.63) | P2RX7 | |
| SCHEMBL20106824 | 0.75 | P2RX7 (0.64) | P2RX7 | |
| SCHEMBL19906526 | 0.75 | P2RX7 (0.62) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287443-A1 | 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Shionogi & Co., Ltd (JP) | 2018-02-28 | — | — | EP | disclosed |