SCHEMBL19907152

SCHEMBL19907152

Cn1ccc2c(Nc3nc(=O)c(F)cn3CC3=CC=C(F)C(Cl)C3)cccc21

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19907409 0.78 P2RX7 (0.77) P2RX7
SCHEMBL19907383 0.78 P2RX7 (0.77) P2RX7
SCHEMBL19907250 0.78 P2RX7 (0.84) P2RX7
SCHEMBL20107114 0.77 P2RX7 (1.00) P2RX7
SCHEMBL19907372 0.73 P2RX7 (0.53) P2RX7
SCHEMBL20106980 0.69 P2RX7 (0.45) P2RX7
SCHEMBL19906543 0.69 P2RX7 (1.00) P2RX7
SCHEMBL20107074 0.63 P2RX7 (0.66) P2RX7
SCHEMBL20107045 0.63 P2RX7 (0.66) P2RX7
SCHEMBL19907355 0.63 P2RX7 (1.00) P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3287443-A1 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Shionogi & Co., Ltd (JP) 2018-02-28 EP disclosed