SCHEMBL199078

SCHEMBL199078

[CH2]CCC(CCCC)CCCCC

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
ALDH1A1 P00352 3/20 0.42
TDP1 Q9NUW8 1/20 0.42
DNM1 Q05193 2/20 0.42
TSHR P16473 3/20 0.41
CYP3A4 P08684 2/20 0.41
OPRM1 P35372 1/20 0.40
CA2 P00918 2/20 0.35
THRB P10828 1/20 0.35
FDPS P14324 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GPR84 Q9NQS5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL101426 0.97 LMNA (0.52) LMNAALDH1A1TDP1DNM1TSHR
SCHEMBL200036 0.97 LMNA (0.52) LMNAALDH1A1TDP1DNM1TSHR
SCHEMBL101074 0.97 LMNA (0.52) LMNAALDH1A1TDP1DNM1TSHR
SCHEMBL101902 0.97 LMNA (0.52) LMNAALDH1A1TDP1DNM1TSHR
SCHEMBL199107 0.97 LMNA (0.52) LMNAALDH1A1TDP1DNM1TSHR
SCHEMBL201404 0.97 LMNA (0.52) LMNAALDH1A1TDP1DNM1TSHR
SCHEMBL103378 0.97 LMNA (0.52) LMNAALDH1A1TDP1DNM1TSHR
SCHEMBL201036 0.97 LMNA (0.52) LMNAALDH1A1TDP1DNM1TSHR
SCHEMBL199400 0.97 LMNA (0.52) LMNAALDH1A1TDP1DNM1TSHR
SCHEMBL101879 0.97 LMNA (0.52) LMNAALDH1A1TDP1DNM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN disclosed
WO-2023085299-A1 CATIONIC LIPID 武田薬品工業株式会社 2023-05-19 WO disclosed
CN-111936559-B Hyperbranched polyesters and their use as wax inhibitors, as pour point depressants, as lubricants or in lubricating oils 巴斯夫欧洲公司 2022-08-30 CN disclosed
EP-3774996-A1 NOVEL HYPERBRANCHED POLYESTERS AND THEIR USE AS WAX INHIBITOR, AS POUR POINT DEPRESSANT, AS LUBRICANT OR IN LUBRICATING OILS BASF SE (DE) 2021-02-17 EP disclosed
US-20210017466-A1 NOVEL HYPERBRANCHED POLYESTERS AND THEIR USE AS WAX INHIBITOR, AS POUR POINT DEPRESSANT, AS LUBRICANT OR IN LUBRICATING OILS BASF SE (DE) 2021-01-21 US disclosed
CN-111936559-A Novel hyperbranched polyesters and their use as wax inhibitors, as pour point depressants, as lubricants or in lubricating oils 巴斯夫欧洲公司 2020-11-13 CN disclosed
WO-2019185401-A1 NOVEL HYPERBRANCHED POLYESTERS AND THEIR USE AS WAX INHIBITOR, AS POUR POINT DEPRESSANT, AS LUBRICANT OR IN LUBRICATING OILS BASF SE (DE) 2019-10-03 WO disclosed
US-8481736-B2 Liquid crystalline rylene tetracarboxylic acid derivatives and use thereof BASF SE (DE) 2013-07-09 US disclosed
US-8088922-B2 Dibenzorylenetetracarboximides as infrared absorbers BASF AKTIENGESELLSCHAFT (DE) 2012-01-03 US disclosed
WO-2011138743-A1 USE OF PYROMELLITIC DIIMIDES IN ORGANIC ELECTRONICS AND ORGANIC PHOTOVOLTAICS BASF SE (DE) 2011-11-10 WO disclosed
WO-1990000052-A1 POLY(AMINOALKYL)AMINOCARBONYL AMINODIOL AMINO ACID DERIVATIVES AS ANTI-HYPERTENSIVE AGENTS G.D. SEARLE & CO. (US) 1990-01-11 WO disclosed
WO-1990000050-A1 AMINOALKYLAMINOCARBONYL AMINODIOL AMINO ACID DERIVATIVES AS ANTI-HYPERTENSIVE AGENTS G.D. SEARLE & CO. (US) 1990-01-11 WO disclosed
EP-0349922-A2 Aminoalkylaminocarbonyl aminodiol amino acid derivatives as anti-hypertensive agents G.D. Searle & Co. (US) 1990-01-10 EP disclosed
EP-0349921-A2 Etheral n-terminal aminodiol amino acid derivatives as anti-hypertensive agents G.D. Searle & Co. (US) 1990-01-10 EP disclosed
US-4877785-A RENIN INHIBITORS G. D. SEARLE & CO. (US) 1989-10-31 US disclosed
EP-0313847-A2 Non-peptidyl alpha-succinamidoacyl aminodiols as anti-hypertensive agents G.D. Searle & Co. (US) 1989-05-03 EP disclosed
EP-0310072-A2 Non-peptidyl beta-succinamidoacyl aminodiols as anti-hypertensive agents G.D. Searle & Co. (US) 1989-04-05 EP disclosed
EP-0310071-A2 Non-peptidyl alpha-aminoacyl aminodiol carbamates as anti-hypertensive agents G.D. Searle & Co. (US) 1989-04-05 EP disclosed
EP-0310073-A2 Non-peptidyl beta-aminoacyl aminodiol carbamates as anti-hypertensive agents G.D. Searle & Co. (US) 1989-04-05 EP disclosed
EP-0310070-A2 Alpha-aminoacyl beta-aminoacyl aminodiols as anti-hypertensive agents G.D. Searle & Co. (US) 1989-04-05 EP disclosed