Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19908074 | 0.93 | P2RX7 (0.69) | P2RX7 | |
| SCHEMBL20107087 | 0.87 | P2RX7 (0.68) | P2RX7 | |
| SCHEMBL19907908 | 0.83 | P2RX7 (0.73) | P2RX7 | |
| SCHEMBL19907839 | 0.83 | P2RX7 (0.78) | P2RX7 | |
| SCHEMBL19907861 | 0.82 | P2RX7 (0.59) | P2RX7 | |
| SCHEMBL19907910 | 0.82 | P2RX7 (0.66) | P2RX7 | |
| SCHEMBL19907620 | 0.82 | P2RX7 (0.76) | P2RX7 | |
| SCHEMBL19907362 | 0.81 | P2RX7 (0.70) | P2RX7 | |
| SCHEMBL19907826 | 0.81 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL23953566 | 0.80 | P2RX7 (0.87) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287443-A1 | 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Shionogi & Co., Ltd (JP) | 2018-02-28 | — | — | EP | disclosed |