Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19908243 | 0.87 | ALK (0.38) | ALK | |
| SCHEMBL1601807 | 0.87 | — | — | |
| SCHEMBL13676586 | 0.79 | ALK (0.38) | ALK | |
| SCHEMBL19908334 | 0.76 | MTOR (0.32) | — | |
| SCHEMBL1601457 | 0.74 | ALK (0.38) | ALK | |
| SCHEMBL12062729 | 0.70 | ALK (0.49) | ALK | |
| SCHEMBL7951142 | 0.70 | LRRK2 (0.33) | ALK | |
| SCHEMBL1602398 | 0.67 | ALK (0.38) | ALK | |
| SCHEMBL17807826 | 0.65 | — | — | |
| SCHEMBL19908318 | 0.64 | ALK (0.39) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091951-B1 | PYRIDO[2,3-B]PYRAZINE AND [1,8]-NAPHTHYRIDINE DERIVATIVES AS ALK AND C-MET INHIBITORS | CEPHALON INC (US) | 2018-02-28 | — | — | EP | disclosed |