Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173790 | 0.89 | APP (0.50) | APPMAPTHPGDPOLBXBP1 | |
| SCHEMBL15871058 | 0.84 | TSHR (0.42) | MAPTHPGDPOLBXBP1HRH3 | |
| SCHEMBL8943750 | 0.84 | MAPT (0.55) | MAPTHPGDPOLBXBP1HRH3 | |
| SCHEMBL17281130 | 0.84 | MAPT (0.53) | MAPTHPGDPOLBXBP1HRH3 | |
| SCHEMBL17281109 | 0.82 | KMT2A (0.43) | MAPTHPGDPOLBXBP1HRH3 | |
| SCHEMBL15871072 | 0.82 | KDM4E (0.48) | APPMAPTHPGDPOLBXBP1 | |
| SCHEMBL123415 | 0.78 | MAPT (0.55) | MAPTHPGDPOLBXBP1KDM4E | |
| SCHEMBL2856507 | 0.77 | CYP3A4 (0.44) | APPKDM4EALDH1A1LMNATSHR | |
| SCHEMBL28553590 | 0.76 | MAPT (0.59) | MAPTPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL19908437 | 0.75 | MAPT (0.41) | APPMAPTHPGDPOLBXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2941474-B1 | HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION | NITTO DENKO CORP (JP) | 2018-02-28 | — | — | EP | disclosed |