SCHEMBL17281130

SCHEMBL17281130

CC(C)COc1ccc(N(c2ccccc2)c2ccc(OCC(C)C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.53
HPGD P15428 3/20 0.53
POLB P06746 2/20 0.53
XBP1 P17861 1/20 0.53
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
ALOX12 P18054 1/20 0.49
LMNA P02545 2/20 0.48
MAOA P21397 1/20 0.44
PTGS1 P23219 1/20 0.44
GPR88 Q9GZN0 1/20 0.43
CYP2C9 P11712 3/20 0.42
CYP2C19 P33261 3/20 0.42
CYP2D6 P10635 3/20 0.42
CYP3A4 P08684 2/20 0.42
NPC1 O15118 1/20 0.42
MTOR P42345 1/20 0.42
TP53 P04637 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15871058 0.85 TSHR (0.42) MAPTHPGDPOLBXBP1MEN1
SCHEMBL8943750 0.85 MAPT (0.55) MAPTHPGDPOLBXBP1MEN1
SCHEMBL8944304 0.84 LMNA (0.44) MAPTHPGDPOLBXBP1LMNA
SCHEMBL19908486 0.84 APP (0.47) MAPTHPGDPOLBXBP1MEN1
SCHEMBL15871072 0.84 KDM4E (0.48) MAPTHPGDPOLBXBP1MEN1
SCHEMBL17281109 0.84 KMT2A (0.43) MAPTHPGDPOLBXBP1MEN1
SCHEMBL9161805 0.82 LMNA (0.40) MAPTHPGDPOLBXBP1MEN1
Propane SCHEMBL27634743 0.82 LMNA (0.63) MAPTHPGDPOLBXBP1MEN1
SCHEMBL97377 0.82 LMNA (0.68) MAPTHPGDPOLBXBP1MEN1
SCHEMBL9178337 0.82 LMNA (0.68) MAPTHPGDPOLBXBP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840397-B2 Highly-fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2020-11-17 US disclosed
US-9960294-B2 Highly fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2018-05-01 US disclosed
EP-2941474-B1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION NITTO DENKO CORP (JP) 2018-02-28 EP disclosed
US-20150340519-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION NITTO DENKO CORPORATION (JP) 2015-11-26 US disclosed
US-20150340519-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION NITTO DENKO CORPORATION (JP) 2015-11-26 US disclosed