Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19908723 | 0.69 | — | — | |
| SCHEMBL19908668 | 0.61 | — | — | |
| SCHEMBL69820 | 0.61 | GABRA1 (0.55) | PTPN1PTPN11ESR1ESR2 | |
| SCHEMBL11296783 | 0.61 | PTPN1 (0.42) | PTPN1PTPN11ESR1ESR2 | |
| SCHEMBL10982245 | 0.60 | PTPN1 (0.38) | PTPN1PTPN11ESR1ESR2 | |
| SCHEMBL5439911 | 0.59 | PTPN1 (0.41) | PTPN1PTPN11ESR1ESR2 | |
| SCHEMBL10870742 | 0.59 | CA12 (0.41) | PTPN1PTPN11ESR1ESR2 | |
| SCHEMBL27816563 | 0.59 | PTPN1 (0.60) | PTPN1PTPN11 | |
| SCHEMBL10994390 | 0.59 | CYP3A4 (0.38) | PTPN1PTPN11ESR1ESR2 | |
| SCHEMBL10883141 | 0.58 | PTPN1 (0.31) | PTPN1PTPN11ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287441-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-28 | — | — | EP | disclosed |