Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 6/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510112 | 0.69 | HPGD (0.46) | HPGDDPP4HSD11B1ALDH1A1LMNA | |
| SCHEMBL12520059 | 0.61 | HPGD (0.52) | HPGDDPP4HSD11B1CTSBCTSS | |
| SCHEMBL3426748 | 0.60 | HPGD (0.61) | HPGDHSD11B1ALDH1A1LMNAHTT | |
| SCHEMBL23708985 | 0.60 | HPGD (0.61) | HPGDHSD11B1ALDH1A1LMNAHTT | |
| SCHEMBL23708986 | 0.60 | HPGD (0.61) | HPGDHSD11B1ALDH1A1LMNAHTT | |
| SCHEMBL17052876 | 0.59 | DPP4 (0.45) | HPGDDPP4LMNAHTT | |
| SCHEMBL12856491 | 0.59 | HPGD (0.79) | HPGDHSD11B1ALDH1A1LMNAHTT | |
| SCHEMBL8518585 | 0.59 | HPGD (0.79) | HPGDHSD11B1ALDH1A1LMNAHTT | |
| SCHEMBL15199115 | 0.59 | HPGD (0.79) | HPGDHSD11B1ALDH1A1LMNAHTT | |
| SCHEMBL18228450 | 0.58 | HPGD (1.00) | HPGDHSD11B1ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287441-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-28 | — | — | EP | disclosed |