Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | DPP4 | P27487 | 7/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25910099 | 0.78 | HRH3 (0.48) | — | |
| SCHEMBL8793144 | 0.71 | HPGD (0.45) | HPGDHSD11B1HTTALDH1A1TSHR | |
| SCHEMBL13502402 | 0.70 | HPGD (0.36) | HPGDDPP4HSD11B1HTTBIRC2 | |
| SCHEMBL19908642 | 0.69 | HPGD (0.39) | HPGDDPP4HSD11B1HTTALDH1A1 | |
| SCHEMBL31125744 | 0.69 | HPGD (0.42) | HPGDDPP4HSD11B1ALDH1A1TSHR | |
| SCHEMBL12332586 | 0.67 | HPGD (0.75) | HPGDHSD11B1HTTALDH1A1TSHR | |
| SCHEMBL8921804 | 0.67 | HPGD (0.75) | HPGDHSD11B1HTTALDH1A1TSHR | |
| SCHEMBL9189999 | 0.66 | HPGD (0.44) | HPGDDPP4ALDH1A1TSHR | |
| SCHEMBL806748 | 0.65 | HPGD (0.95) | HPGDHSD11B1HTTALDH1A1TSHR | |
| SCHEMBL19658219 | 0.65 | HPGD (0.95) | HPGDHSD11B1HTTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254545-B1 | DIAMINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-06 | — | — | EP | disclosed |
| EP-0254545-A2 | Diamine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-27 | — | — | EP | disclosed |