Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 3/20 | 0.52 |
| ▸ | ACE | P12821 | 6/20 | 0.51 |
| ▸ | REN | P00797 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19908871 | 1.00 | PEPD (0.52) | PEPDACERENKDM4EF2 | |
| SCHEMBL18124445 | 0.87 | PEPD (0.53) | PEPDACERENKDM4EF2 | |
| SCHEMBL27015252 | 0.87 | PEPD (0.53) | PEPDACERENKDM4EF2 | |
| SCHEMBL18595211 | 0.87 | PEPD (0.53) | PEPDACERENKDM4EF2 | |
| SCHEMBL38660845 | 0.85 | ACE (0.71) | PEPDACERENKDM4EF2 | |
| SCHEMBL15223625 | 0.85 | PEPD (0.52) | PEPDACERENKDM4EF2 | |
| SCHEMBL28545395 | 0.85 | ACE (0.71) | PEPDACERENKDM4EF2 | |
| SCHEMBL683116 | 0.85 | ACE (0.71) | PEPDACERENKDM4EF2 | |
| SCHEMBL21533006 | 0.85 | ACE (0.71) | PEPDACERENKDM4EF2 | |
| SCHEMBL12191496 | 0.85 | PEPD (0.52) | PEPDACERENKDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205552-B1 | CRYSTALLINE POLYMORPH OF THE SELECTIVE ANDROGEN MODULATORS (R) OR (S)-N-(4-CYANO-3-(TRIFLUOROMETHYL)PHENYL)-3-(4-CYANOPHENOXY)-2-HYDROXY-2-METHYLPROPANAMIDE | GTX INC (US) | 2018-02-28 | — | — | EP | disclosed |