Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.71 |
| ▸ | REN | P00797 | 4/20 | 0.71 |
| ▸ | PEPD | P12955 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | F2 | P00734 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | LTA4H | P09960 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.71 |
| ▸ | HTR2A | P28223 | 1/20 | 0.71 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.71 |
| ▸ | HRH1 | P35367 | 1/20 | 0.71 |
| ▸ | THPO | P40225 | 1/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.71 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28545395 | 1.00 | ACE (0.71) | ACERENPEPDKDM4EF2 | |
| SCHEMBL28545392 | 1.00 | ACE (0.71) | ACERENPEPDKDM4EF2 | |
| SCHEMBL38660845 | 1.00 | ACE (0.71) | ACERENPEPDKDM4EF2 | |
| SCHEMBL21533006 | 1.00 | ACE (0.71) | ACERENPEPDKDM4EF2 | |
| SCHEMBL10511283 | 0.90 | ACE (0.73) | ACERENPEPDKDM4EF2 | |
| SCHEMBL11548034 | 0.88 | ACE (0.56) | ACERENPEPDKDM4EF2 | |
| SCHEMBL24360326 | 0.87 | ACE (0.69) | ACERENPEPDKDM4EF2 | |
| SCHEMBL18124445 | 0.87 | PEPD (0.53) | ACERENPEPDKDM4EF2 | |
| SCHEMBL18595211 | 0.87 | PEPD (0.53) | ACERENPEPDKDM4EF2 | |
| SCHEMBL27015252 | 0.87 | PEPD (0.53) | ACERENPEPDKDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178351-A | Flavanol captopril derivative and synthetic method and application thereof | 沈阳药科大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-112526056-B | Separation and detection method of captopril and diastereoisomer thereof | 江苏晶立信医药科技有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-112526056-A | Separation and detection method of captopril and diastereoisomer thereof | 江苏晶立信医药科技有限公司 | 2021-03-19 | — | — | CN | disclosed |
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110046090-A1 | MODULATION OF NEUROGENESIS WITH GABA AGENTS AND GABA ANALOGS | BRAINCELLS INC. (US) | 2011-02-24 | — | — | US | disclosed |
| US-20110046090-A1 | MODULATION OF NEUROGENESIS WITH GABA AGENTS AND GABA ANALOGS | BRAINCELLS INC. (US) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046090-A1 | MODULATION OF NEUROGENESIS WITH GABA AGENTS AND GABA ANALOGS | GAP43, GABRB1, GABRB3 | ACE 4514/4885REN 4301/4885PEPD 4236/4885 |
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | ACE 6/4885REN 15/4885PEPD 366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.