SCHEMBL19909618

SCHEMBL19909618

COCCN(CC(C)C)C(C)C

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.58
KCNA5 P22460 2/20 0.34
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10289399 0.85 PIK3CD (0.48) PIK3CDKCNA5RAB9A
SCHEMBL13995359 0.84 PIK3CD (0.50) PIK3CDKCNA5RAB9A
SCHEMBL17914506 0.79 PIK3CD (0.35) PIK3CD
SCHEMBL4733460 0.78 PIK3CD (0.43) PIK3CDKCNA5RAB9A
SCHEMBL12703399 0.76 KCNA5 (0.43) PIK3CDKCNA5RAB9A
SCHEMBL19083710 0.76 PIK3CD (0.41) PIK3CDKCNA5RAB9A
SCHEMBL18232147 0.75 PIK3CD (0.62) PIK3CD
SCHEMBL24578095 0.74 PIK3CD (0.40) PIK3CDKCNA5RAB9A
SCHEMBL5535647 0.74 PIK3CD (0.40) PIK3CDKCNA5RAB9A
SCHEMBL5535641 0.74 PIK3CD (0.40) PIK3CDKCNA5RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3081562-B1 COMPOUND FOR INHIBITING ACTIVITY OF GLUTATHIONE S-TRANSFERASE OMEGA 1 AND PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUND UNIV CHINA MEDICAL (TW) 2018-02-28 EP disclosed