Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPX4 | P36969 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 8/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19909717 | 0.77 | GPX4 (0.33) | GPX4BTKNSD2 | |
| SCHEMBL16122876 | 0.76 | BTK (0.38) | BTK | |
| SCHEMBL16078763 | 0.74 | GPX4 (0.37) | GPX4BTK | |
| SCHEMBL16075248 | 0.74 | BTK (0.33) | GPX4BTK | |
| SCHEMBL2593681 | 0.73 | SMN1; SMN2 (0.45) | NAMPT | |
| SCHEMBL30059414 | 0.72 | NAMPT (0.36) | NAMPT | |
| SCHEMBL16075032 | 0.72 | BTK (0.42) | GPX4BTK | |
| SCHEMBL15472834 | 0.72 | BTK (0.39) | BTK | |
| Hydrochloric Acid SCHEMBL16454452 | 0.71 | SMN1; SMN2 (0.43) | NAMPT | |
| SCHEMBL2239249 | 0.70 | NAMPT (0.36) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970163-B1 | 5-THIAZOLECARBOXAMIDE DERVATIVES AND THEIR USE AS BTK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2018-02-28 | — | — | EP | disclosed |