Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16078890 | 0.79 | GPR183 (0.34) | — | |
| SCHEMBL16075243 | 0.79 | CRHBP (0.31) | — | |
| SCHEMBL19909730 | 0.78 | NAMPT (0.31) | — | |
| SCHEMBL16127680 | 0.78 | JAK3 (0.42) | USP2 | |
| SCHEMBL16122875 | 0.77 | BTK (0.35) | — | |
| SCHEMBL16127676 | 0.75 | BTK (0.38) | — | |
| SCHEMBL14682662 | 0.75 | DPP4 (0.33) | — | |
| SCHEMBL21319714 | 0.73 | CHRM4 (0.30) | — | |
| SCHEMBL16074990 | 0.73 | BTK (0.32) | — | |
| SCHEMBL16074978 | 0.73 | BTK (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970163-B1 | 5-THIAZOLECARBOXAMIDE DERVATIVES AND THEIR USE AS BTK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2018-02-28 | — | — | EP | disclosed |